Neonatal and Adult Rabbit Renal Brush Border Membrane Vesicle Solute Reflection Coefficients
نویسندگان
چکیده
منابع مشابه
Glucocorticoids increase osmotic water permeability (Pf) of neonatal rabbit renal brush border membrane vesicles.
During postnatal maturation, there is an increase in renal brush border membrane vesicle (BBMV) osmotic water permeability and a parallel increase in aquaporin-1 (AQP1) protein abundance. The mechanisms responsible for these changes remain unknown. Because serum glucocorticoid levels rise postnatally and have previously been linked to other maturational changes in renal function, we examined th...
متن کاملDetection of renal brush border membrane enzymes for evaluation of renal injury in neonatal scleredema
OBJECTIVE To evaluate renal brush border membrane enzymes in urine as an indicator for renal injury in neonatal scleredema (NS). METHODS Sixty nine NS patients in our hospital were enrolled and divided into mild group and moderate/severe group. Patients were further randomly divided into therapy and control subgroups for 7 days ligustrazine administration. Urine samples were collected to dete...
متن کاملHeterogeneity of rabbit intestine brush border plasma membrane cholesterol.
Nonspecific lipid transfer protein accelerated cholesterol exchange from brush border vesicles according to a biphasic time course, but sonicated vesicles made from brush border phospholipids and glycosphingolipids showed a single phase exchange. Removal of surface protein with papain or opening brush border vesicles with deoxycholate did not abolish the biphasic exchange pattern. In brush bord...
متن کاملbrush-border membrane vesicles
The characteristics of hypoxanthine transport were examined in purified brush-border membrane vesicles isolated from guineapig kidney. Hypoxanthine uptake in the vesicles was specifically stimulated by both Na+ and an inside-negative potential, resulting in a transient accumulation of intravesicular hypoxanthine. Na+-dependent hypoxanthine influx was saturable (apparent Km 4.4 + 2.1 ,uM, Vmax 1...
متن کاملOntogeny of Na/H antiporter activity in rabbit renal brush border membrane vesicles.
The development of the Na/H antiporter was studied in renal brush border membrane vesicles (BBMV) from fetal and adult rabbits using isotopic and fluorescent techniques. The kinetics of the antiporter studied by 22Na+ uptake revealed that the Vmax was only 25% of that in the adult; however, the Km's for Na+ were not significantly different. These data were confirmed by a fluorescent assay using...
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ژورنال
عنوان ژورنال: Neonatology
سال: 1999
ISSN: 1661-7800,1661-7819
DOI: 10.1159/000014148